2-Chloroquinolin-8-ol

CAS: 31568-91-9

Ref. 3D-FC130042

Informação sobre produto

• Nome: 2-Chloroquinolin-8-ol
• Sinónimos: 8-quinolinol, 2-chloro-, 8-Quinolinol, 2-Chloro-

Descrição

2-Chloroquinolin-8-ol is a chemical compound that binds to the human serum albumin and has cytotoxic effects on cancer cells. It has been shown to be an inhibitor of survivin, a protein that can promote cancer cell survival. 2-Chloroquinolin-8-ol has also been shown to inhibit the proliferation of human epidermoid carcinoma cells in vitro. This agent also inhibits the growth of Trichophyton mentagrophytes, a fungus that causes tinea versicolor, by binding to the ribosomal RNA. The binding constants for 2-chloroquinolin-8-ol were determined using atomic orbital calculations and vibrational spectroscopy. It has also been shown to bind with high affinity to hepg2 cells and cervical cancer cells.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 179.6 g/mol
• Fórmula: C₉H₆ClNO
• Pureza: Min. 95%
• InChI: InChI=1S/C9H6ClNO/c10-8-5-4-6-2-1-3-7(12)9(6)11-8/h1-5,12H
• Chave InChI: InChIKey=HNUFDBQIXGQAEX-UHFFFAOYSA-N
• SMILES: Oc1cccc2ccc(Cl)nc12