5-(Chlorosulfonyl)-2-methylbenzoic acid
CAS: 89001-57-0
Ref. 3D-FC140651
1g | A consultar | ||
2g | A consultar | ||
5g | A consultar | ||
10g | A consultar | ||
25g | A consultar |
Informação sobre produto
- 2-Methyl-5-(chlorosulfonyl)benzoic acid
- 3-Carboxy-4-methylbenzenesulfonyl chloride
- 5-(Chlorosulfonyl)-2-methylbenzenecarboxylic acid
- 5-(Chlorosulphonyl)-2-methylbenzoic acid
- Benzoic acid, 5-(chlorosulfonyl)-2-methyl-
- NSC 210248
- Wsgr D1 Cvq
5-(Chlorosulfonyl)-2-methylbenzoic acid (5CSMB) is a potent inhibitor of the enzyme 2-hydroxyglutarate dehydrogenase. This compound has been shown to be effective in inhibiting the uptake of fluorine-18-labeled 2-hydroxyglutarate into the liver and biliary tract, which is a marker for β-ketothiolase activity. 5CSMB has also been shown to bind to other enzymes involved in the synthesis of glutathione, such as glutathione synthase, glutathione reductase, and glutathione peroxidase. The binding of 5CSMB inhibits the production of glutathione and leads to cell death by apoptosis.
5CSMB can be radiolabeled with fluorine-18 for positron emission tomography (PET) imaging studies. The results from this study show that 5CSMB binds specifically to hepatobiliary β-
Propriedades químicas
Consulta técnica sobre: 3D-FC140651 5-(Chlorosulfonyl)-2-methylbenzoic acid
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.