6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

CAS: 1824-52-8

Ref. 3D-FC145398

Informação sobre produto

• Nome: 6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Sinónimos: Bemetizide
• Marca: Biosynth
• Descrição: 6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide is an active metabolite of the drug benzbromarone. It is primarily administered as a diuretic to treat high blood pressure and congestive heart failure. The pharmacodynamics of this drug are related to its ability to inhibit the activity of sodium channels in vascular smooth muscle cells and thereby reduce the force of contraction and relax the vessel wall. 6CBDMTD has shown an increase in glomerular filtration rate in patients with congestive heart failure. This drug also decreases the plasma concentration of fatty acids by inhibiting the formation of lipoprotein particles. 6CBDMTD has been shown to be effective at lowering diastolic and systolic blood pressure levels in patients with hypertension.

Propriedades químicas

• Peso molecular: 401.89 g/mol
• Fórmula: C₁₅H₁₆ClN₃O₄S₂
• Pureza: Min. 95%
• InChI: InChI=1S/C15H16ClN3O4S2/c1-9(10-5-3-2-4-6-10)15-18-12-7-11(16)13(24(17,20)21)8-14(12)25(22,23)19-15/h2-9,15,18-19H,1H3,(H2,17,20,21)
• Chave InChI: InChIKey=PYVUMAGVCSQCBD-UHFFFAOYSA-N
• SMILES: CC(c1ccccc1)C1Nc2cc(Cl)c(S(N)(=O)=O)cc2S(=O)(=O)N1