Cevimeline, hydrochloridesalt
CAS: 107233-08-9
Ref. 3D-FC146883
1mg | Descontinuado | ||
2mg | Descontinuado | ||
5mg | Descontinuado | ||
10mg | Descontinuado | ||
25mg | Descontinuado |
Informação sobre produto
- (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]
- (±)-cis-2-Methylspiro[1,3-oxathiolane-5,3′-quinuclidine]
- 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine
- Af 102B
- Cevimeline [INN]
- Fks 508
- Hsdb 7286
- Sni 2011
- Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, (2'R,3R)-rel-
- Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, cis-
- Ver mais sinónimos
- Spiro[1-azabicyclo[2.2.2]octane-3,5′-[1,3]oxathiolane], 2′-methyl-, (2′R,3R)-rel-
- Unii-K9V0Cdq56E
- rel-(2′R,3R)-2′-Methylspiro[1-azabicyclo[2.2.2]octane-3,5′-[1,3]oxathiolane]
- Cevimeline
Cevimeline is a cholinergic agent that is used to treat salivary gland dysfunction in geriatric patients and autoimmune diseases. It has been shown to have a significant effect on the secretion of saliva, which may be due to its ability to stimulate the muscarinic receptor. Cevimeline hydrochloride has been shown to be effective against radiation-induced xerostomia and may also be used as an adjunct therapy for chronic oral mucositis induced by cancer chemotherapy. It has been found that cevimeline induces transcriptional regulation of a number of genes, including those involved in skin cancer and chronic oral inflammation.