4-Chloro-3-pyridinesulfonamide

CAS: 33263-43-3

Ref. 3D-FC147010

Informação sobre produto

• Nome: 4-Chloro-3-pyridinesulfonamide
• Sinónimos: 3-Pyridinesulfonamide, 4-chloro-, 4-Chloro-3-Pyridine Sulfonamide, 4-Chloro-3-pyridylsulfonamide, 4-Chloropyridine-3-Sulfamide, 4-Chloropyridine-3-sulfonamide

Descrição

4-Chloro-3-pyridinesulfonamide is an antibacterial sulfonamide that inhibits the enzyme carbonic anhydrase. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The anticancer effect may be due to its ability to block the growth of cancer cells by interfering with DNA synthesis and inducing apoptosis, which causes cell death. 4-Chloro-3-pyridinesulfonamide also inhibits tuberculosis and tuberculostatic activity may be due to its inhibition of mycobacterium tuberculosis ribosomes. 4-Chloro-3-pyridinesulfonamide binds to the active site of bacterial anhydrase as well as human carbonic anhydrase II, blocking the conversion of CO2 into bicarbonate ions, which leads to a decrease in pH. This drug also binds to DNA and RNA, inhibiting DNA synthesis and RNA synthesis respectively, leading to cell

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 192.62 g/mol
• Fórmula: C₅H₅ClN₂O₂S
• Pureza: Min. 95%
• Cor/forma: Solid