3-Chloropyridazine-4-carbonitrile
CAS: 1445-56-3
Ref. 3D-FC156406
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Informação sobre produto
- 3-Chloro-4-pyridazinecarbonitrile
- 4-Cyano-3-chloropyridazine
- 4-Pyridazinecarbonitrile, 3-Chloro-
3-Chloropyridazine-4-carbonitrile is an acridone that has been shown to be an effective antibacterial agent. It was synthesized by the intramolecular Diels-Alder reaction of pyridine and 1,3-butadiene, followed by a sequence of reactions involving thioxanthones. 3-Chloropyridazine-4-carbonitrile binds to the bacterial enzyme 50S ribosomal subunit by competitive inhibition and prevents the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. 3-Chloropyridazine-4-carbonitrile also has shown activity against methicillin resistant Staphylococcus aureus strains.
Propriedades químicas
Consulta técnica sobre: 3D-FC156406 3-Chloropyridazine-4-carbonitrile
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