3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone

CAS: 77439-76-0

Ref. 3D-FC20076

Informação sobre produto

• Nome: 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
• Sinónimos: MXMX (bacterial mutagen)Mutagen X, 2(5H)-Furanone, 3-chloro-4-(dichloromethyl)-5-hydroxy-, 3-Chloro-4-(dichloromethyl)-5-hydroxy-2,5-dihydrofuran-2-one, 3-chloro-4-(dichloromethyl)-5-hydroxy-*2(5H)-fura, MX (bacterial mutagen), Mutagen X

Descrição

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone belongs to the class of polymerase chain inhibitors. It inhibits DNA synthesis by binding to the enzyme DNA polymerase and blocking the progression of DNA synthesis. 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone has significant cytotoxicity in mammalian cells and is genotoxic, which may be due to its mutagenicity. The mechanism of its mutagenicity is not known, but it has been shown that this compound reacts with effector proteins such as thiols and sulfhydryls. 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone can react with chlorine in water to form a chlorinated derivative that is more stable than the parent compound. This chemical stability has been used

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 217.43 g/mol
• Fórmula: C₅H₃Cl₃O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C5H3Cl3O3/c6-2-1(3(7)8)4(9)11-5(2)10/h3-4,9H
• Chave InChI: InChIKey=WNTRMRXAGJOLCU-UHFFFAOYSA-N
• SMILES: O=C1OC(O)C(C(Cl)Cl)=C1Cl