4-Chloro pyrazole

CAS: 15878-00-9

Ref. 3D-FC32604

Informação sobre produto

• Nome: 4-Chloro pyrazole
• Sinónimos: 1H-Pyrazole, 4-chloro-, 4-Chloro-1H-Pyrazol, 4-Chloro-1H-Pyrazole, 4-Chloro-Pyrazol, Akos B001464, Art-Chem-Bb B001464, Pyrazole, 4-chloro-, Vitas-Bb Tbb000653, 4-Chloropyrazole

Descrição

4-Chloro pyrazole is a pyrazole derivative that has been shown to be effective as an inhibitor of aldehyde dehydrogenase. The structural formula for 4-chloro pyrazole is shown below. This compound binds to the active site of the enzyme, preventing it from catalyzing the conversion of acetaldehyde into acetic acid and thus preventing the accumulation of acetaldehyde in cells. The binding site is thought to involve a nucleophilic attack by the chlorine atom on the carbonyl group at C4 on the pyrazole ring, followed by coordination with two oxygens from water molecules. The chemical analyses indicate that 4-chloro pyrazole is not readily metabolized, which may be due to its inertness as a substrate for various enzymes or its low solubility in biological fluids.
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[[File:4-Chloro Pyrazole Structure.png|thumb|center|500px|Struct

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 102.52 g/mol
• Fórmula: C₃H₃ClN₂
• Pureza: Min. 95%
• Cor/forma: Off-White Powder