Ceftizoxime

CAS: 68401-81-0

Ref. 3D-FC40907

Informação sobre produto

• Nome: Ceftizoxime
• Sinónimos: (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-, 7-[[(2Z)-2-(2-azaniumylidene-3H-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Ceftisomin, Ceftizoxime acid, Epocelin

Descrição

Ceftizoxime is a cephalosporin antibiotic that is used to treat infections caused by Gram-negative bacteria. Ceftizoxime binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. It also has a neurokinin-1 receptor antagonist effect, which may be related to its efficacy against infections of the central nervous system. Ceftizoxime has been shown to have a high affinity for extravascular sites and it has good oral bioavailability. The half-life of ceftizoxime is 2 to 3 hours in adults and 1 hour in children due to rapid elimination from body tissues. The drug can be given intravenously or orally as a prodrug. In vitro experiments have shown that ceftizoxime can inhibit polymerase chain

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 383.41 g/mol
• Fórmula: C₁₃H₁₃N₅O₅S₂
• Pureza: Min. 95%
• Cor/forma: Powder