Informação sobre produto
- o-Chlorobenzaldoxime
- 2-Chlorobenzaldoxime
- 2-Chlorobenzenecarbaldehyde Oxime
- Benzaldehyde, 2-chloro-, oxime
- Benzaldehyde, o-chloro-, oxime
- NSC 61415
- o-Chlorobenzaldehyde Oxime
2-Chlorobenzaldehyde oxime is a compound that inhibits the growth of mycobacterium tuberculosis. It reacts with chloride in the environment to form 2-chlorobenzaldehyde, which reacts with an isoxazole to produce a quinone. Quinones are toxic to mammals and are thought to be responsible for the antimycobacterial activity of this compound. The reaction mechanism of 2-chlorobenzaldehyde oxime has been studied using various techniques and its toxicity has been evaluated in both culture and animal studies. This compound has shown no significant effects on mice at up to 100 mg/kg body weight, but it was found to cause death in rats at doses as low as 0.1 mg/kg body weight.
2-Chlorobenzaldehyde oxime was synthesised by reacting 2-chlorobenzaldehyde with oxalyl chloride under conditions suitable for safety, and the product was purified by recrystallisation from acetone. The synthesis
Propriedades químicas
Consulta técnica sobre: 3D-FC53579 2-Chlorobenzaldehyde oxime
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