7-Chloroquinoxaline

CAS: 5448-43-1

Ref. 3D-FC66699

Informação sobre produto

• Nome: 7-Chloroquinoxaline
• Sinónimos: 6-Chloroquinoxaline, Quinoxaline, 6-chloro-
• CAS: 5448-43-1

Descrição

7-Chloroquinoxaline is a nucleophilic compound that can be synthesized by reductive chlorination of 7-chloroquinoline. 7-Chloroquinoxaline has been shown to have anticancer activity in vitro, as well as the ability to inhibit the proliferation of human breast cancer cells (MCF-7) in culture. It also inhibits glyoxalase I and II, which are enzymes that catalyze the conversion of glyoxal to D-lactate and H2O2. This inhibition may be due to its ability to react with the C=N bond at carbon 2 of dimethylformamide (DMF), forming a covalent adduct with DMF and an anticancer agent such as methotrexate or 5-fluorouracil. The formation of this conjugate would result in a decrease in DMF concentration, leading to decreased production of H2O2 and increased levels of D-l

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 164.59 g/mol
• Fórmula: C₈H₅ClN₂
• Pureza: Min. 95%
• InChI: InChI=1S/C8H5ClN2/c9-6-1-2-7-8(5-6)11-4-3-10-7/h1-5H
• Chave InChI: InChIKey=HOOMNCITVCXDTR-UHFFFAOYSA-N
• SMILES: Clc1ccc2nccnc2c1