3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one

CAS: 252742-72-6

Ref. 3D-FC72032

Informação sobre produto

• Nome: 3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one
• Sinónimos: 3H-1,2,4-Triazol-3-one, 5-(chloromethyl)-1,2-dihydro-, 5-(Chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one, 5-(chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one, 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one, 5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one, 5-Chloromethyl-2H-1,2,4-triazolin-3-one

Descrição

3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one is a synthetic organic compound that is used as a reagent in organic synthesis. It can be prepared by the reaction of hydrochloric acid and chloromethyl methyl ether with sodium hydroxide. 3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one is used in the industrial production of aprepitant, a drug for the prevention and treatment of nausea and vomiting caused by cancer drugs. The pharmacological activity of 3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one has been studied extensively. It is an inhibitor of cytochrome P450 enzymes and acts as an acylation agent by reacting with alcohols to form esters. 3-(Chloromethyl)-1H-1

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 237 g/mol
• Fórmula: C₃H₄CIN₃O
• Pureza: Min. 95%