2-Chloro-6-Fluoro-4-Methylquinoline

CAS: 18529-12-9

Ref. 3D-FC82197

Informação sobre produto

• Nome: 2-Chloro-6-Fluoro-4-Methylquinoline
• Sinónimos: Quinoline, 2-Chloro-6-Fluoro-4-Methyl-

Descrição

2-Chloro-6-Fluoro-4-Methylquinoline is a quinoline derivative that has been shown to be mutagenic. It is metabolized by the liver into an enamine, which reacts with oxygen to form a mutagenic epoxide. This compound is metabolized through a number of metabolic transformations, including oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-Chloro-6-Fluoro-4-Methylquinoline also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 195.62 g/mol
• Fórmula: C₁₀H₇ClFN
• Pureza: Min. 95%
• InChI: InChI=1S/C10H7ClFN/c1-6-4-10(11)13-9-3-2-7(12)5-8(6)9/h2-5H,1H3
• Chave InChI: InChIKey=NWUZTEJFFHETQP-UHFFFAOYSA-N
• SMILES: Cc1cc(Cl)nc2ccc(F)cc12