1,3-Dimethyluracil

CAS: 874-14-6

Ref. 3D-FD06288

Informação sobre produto

• Nome: 1,3-Dimethyluracil
• Sinónimos: 1,3-Dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1,3-Dimethyl-1H,3H-pyrimidine-2,4-dione, 1,3-Dimethyl-2,4(1H,3H)-pyrimidinedione, 1,3-Dimethyl-2,4-Pyrimidinedione, 1,3-dimethylpyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-, N,N′-Dimethyluracil, N¹,N³-Dimethyluracil, NSC 401858, Uracil, 1,3-dimethyl-

Descrição

1,3-Dimethyluracil is a uracil derivative that is used as a hydrogen-bond donor, which helps to repair DNA. It has been shown to have a kinetic isotope effect in the deuterium isotope effect studies. The carbonyl group of 1,3-dimethyluracil can form hydrogen bonds with the guanine base in DNA and lead to the formation of an adduct. This adduct can be repaired by nucleotide excision repair when it forms a dimer with another 1,3-dimethyluracol molecule or by base excision repair when it forms a dimer with another purine or pyrimidine base.
Aqueous solutions of 1,3-dimethyluracil are stable for short periods of time but decompose rapidly on heating. X-ray crystal structures show that 1,3-dimethyluracil binds to hydrochloric acid and x-ray crystallographic analysis

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 140.14 g/mol
• Fórmula: C₆H₈N₂O₂
• Pureza: Min. 95%
• Cor/forma: Off-White Slightly Brown Powder
• InChI: InChI=1S/C6H8N2O2/c1-7-4-3-5(9)8(2)6(7)10/h3-4H,1-2H3
• Chave InChI: InChIKey=JSDBKAHWADVXFU-UHFFFAOYSA-N
• SMILES: Cn1ccc(=O)n(C)c1=O