4,4-Difluorocyclohexan-1-one

CAS: 22515-18-0

Ref. 3D-FD104427

Informação sobre produto

• Nome: 4,4-Difluorocyclohexan-1-one
• Sinónimos: 4,4-Difluorocyclohexan-1-One, Cyclohexanone, 4,4-difluoro-

Descrição

4,4-Difluorocyclohexan-1-one (DFCO) is a colorless liquid that is soluble in organic solvents. It has been shown to have potential as a treatment for Alzheimer's disease due to its ability to inhibit the conformational changes in the amyloid beta peptide. DFCO was synthesized by reacting pyridazine with difluoroethanol, which led to the formation of two stereoisomers: R and S. The R stereoisomer was found to be more potent than the S stereoisomer in inhibiting acetylcholine release from human lung cells and had better binding affinity for adenosine receptors. This compound also showed antiinflammatory properties when it was used as an inhibitor of prostaglandin synthesis in mice.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 134.12 g/mol
• Fórmula: C₆H₈F₂O
• Pureza: Min. 95%
• Cor/forma: White Powder
• InChI: InChI=1S/C6H8F2O/c7-6(8)3-1-5(9)2-4-6/h1-4H2
• Chave InChI: InChIKey=NYYSPVRERVXMLJ-UHFFFAOYSA-N
• SMILES: O=C1CCC(F)(F)CC1