β,β-Dimethylacrylalkannin
CAS: 34539-65-6
Ref. 3D-FD145211
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Informação sobre produto
- 3-Methyl-2-butenoic acid (S)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester
- 2-butenoic acid, 3-methyl-, (1S)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester
- beta,beta-Dimethylacrylalkannin
- Dimethylacrylalkannin, β,β-
Beta,beta-dimethylacrylalkannin (DMAA) is a natural compound that has been shown to be cytotoxic to leukemia cells in vitro. DMAA is a diterpene that belongs to the naphthoquinone class of compounds. It damages DNA by inhibiting topoisomerase I and II, which are enzymes that maintain the integrity of DNA. DMAA can also inhibit DNA synthesis and cause strand breakage. DMAA inhibits topoisomerase I and II in both human leukemia cells and Escherichia coli. The cytotoxicity of this compound has been demonstrated in vitro at nanomolar concentrations.
Propriedades químicas
Consulta técnica sobre: 3D-FD145211 β,β-Dimethylacrylalkannin
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