1,3-Dimethyluracil-5-carboxaldehyde
CAS: 4869-46-9
Ref. 3D-FD147434
| 1g | Descontinuado | ||
| 2g | Descontinuado | ||
| 100mg | Descontinuado | ||
| 250mg | Descontinuado | ||
| 500mg | Descontinuado |
Informação sobre produto
Nome:
1,3-Dimethyluracil-5-carboxaldehyde
Sinónimos:
- 1,3-Dimethyl-5-formyluracil
- 1,3-DiMe-5-FormU
- 5-Pyrimidinecarboxaldehyde, 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-
- 1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbaldehyde
Descrição:
1,3-Dimethyluracol-5-carboxaldehyde is an amide of 1,3-dimethyluracil and 5-carboxaldehyde. It has been shown to be an effective radiation sensitizer for the treatment of lymphoblastic leukemia cells in culture. 1,3-Dimethyluracil-5-carboxaldehyde binds to DNA and alters the conformation of the molecule so that it can't be read by the ribosome. This inhibits protein synthesis and causes cell death. The drug also conjugates with DNA to form a covalent bond which causes double strand breaks in the DNA strands. The drug deprotonates at physiological pH levels and reacts with 6-methyluracil to form oxetane derivatives. These compounds are then excreted in urine as quinolizidine alkaloids.
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
168.15 g/mol
Fórmula:
C7H8N2O3
Pureza:
Min. 95%
InChI:
InChI=1S/C7H8N2O3/c1-8-3-5(4-10)6(11)9(2)7(8)12/h3-4H,1-2H3
Chave InChI:
InChIKey=KGJFRZOATIXYPW-UHFFFAOYSA-N
SMILES:
Cn1cc(C=O)c(=O)n(C)c1=O
MDL:
Ponto de fusão:
Ponto de ebulição:
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Densidade:
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Merck:
Código HS:
