1,2-Dimethylindole-3-carboxylicacid
CAS: 20357-15-7
Ref. 3D-FD149422
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Informação sobre produto
- 1,2-Dimethyl-1H-indole-3-carboxylic acid
- 1,2-dimethyl-1H-indole-3-carboxylate
- 1H-Indole-3-carboxylic acid, 1,2-dimethyl-
- Indole-3-carboxylic acid, 1,2-dimethyl-
1,2-Dimethylindole-3-carboxylicacid is a synthetic compound that has been extensively screened for antiviral activity and found to be effective against hepatitis C virus. It inhibits HMG-CoA reductase by binding to the active site of the enzyme, inhibiting its ability to catalyze the conversion of HMG-CoA to mevalonate. This leads to reduced synthesis of sterols, which are necessary for lipid biosynthesis and cell membrane biogenesis. 1,2-Dimethylindole-3-carboxylicacid is stereoselectively active at the (R) enantiomer. The drug also has hepatoselective effects in animal models.
1,2-Dimethylindole-3-carboxylicacid is a linker analog of pyrazoles that have been shown to have antiinflammatory properties in human cells grown in culture. Efflux of this drug from cells may be due to increased
Propriedades químicas
Consulta técnica sobre: 3D-FD149422 1,2-Dimethylindole-3-carboxylicacid
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