Informação sobre produto
- 1-Propanol, 3-[[2-[(1H-benzimidazol-2-ylthio)methyl]-3-methyl-4-pyridinyl]oxy]-
- 2-[[[4-(3-Hydroxypropoxy)-3-methyl-2-pyridyl]methyl]thio]-1H-benzimidazole
- 3-({2-[(1H-benzimidazol-2-ylsulfanyl)methyl]-3-methylpyridin-4-yl}oxy)propan-1-ol
- 3-[[2-[(1H-Benzimidazol-2-ylthio)methyl]-3-methyl-4-pyridinyl]oxy]-1-propanol
Rabeprazole is a proton pump inhibitor (PPI) that inhibits the secretion of stomach acid. It is a racemic mixture of two enantiomers, desmethyl rabeprazole and thiomethyl rabeprazole. The pharmacokinetics of rabeprazole have been determined in healthy Chinese subjects and in human urine using liquid chromatography-mass spectrometry (LC-MS). These experiments showed that desmethyl rabeprazole has a longer half-life than thiomethyl rabeprazole. In addition, the LC-MS parameters were used to calculate the pharmacokinetic parameters of both enantiomers. Rabeprazole has been shown to inhibit donepezil metabolism, which may result in an increased exposure to donepezil.
Propriedades químicas
Consulta técnica sobre: 3D-FD150272 Desmethyl rabeprazolethioether
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