Desethyl chloroquine

CAS: 1476-52-4

Ref. 3D-FD21174

Informação sobre produto

• Nome: Desethyl chloroquine
• Sinónimos: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamineDeethylchloroquineMonodeethylchloroquine, (±)-Desethylchloroquine, 1,4-Pentanediamine N4-(7-chloro-4-quinolinyl)-N1-ethyl-, 1,4-Pentanediamine, N⁴-(7-chloro-4-quinolinyl)-N¹-ethyl-, 4-[[1-Methyl-4-((ethylamino)butyl]amino)]-7-chloroquinoline, 7-Chloro-4-(4-N-ethylamino-1-methylbutylamino)quinoline, Chloroquine, deethyl-, Deethylchloroquine, Monodeethylchloroquine, Monodesethylchloroquine, N-Deethylchloroquine, N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine, N⁴-(7-Chloro-4-quinolinyl)-N¹-ethyl-1,4-pentanediamine, Nsc 13254, N~4~-(7-chloroquinolin-4-yl)-N~1~-ethylpentane-1,4-diamine, Quinoline, 7-chloro-4-[[4-(ethylamino)-1-methylbutyl]amino]-, Wr 29623

Descrição

Desethyl chloroquine is a drug that is used to treat malaria and other infectious diseases. It is an antimalarial drug that has been shown to be effective in the treatment of malaria and related diseases such as toxoplasmosis, amebiasis, trypanosomiasis, and leishmaniasis. Methods for the preparation of desethyl chloroquine are described in the analytical section. To measure the concentration of desethyl chloroquine in blood, it is recommended to collect a sample of blood by venipuncture or fingerstick. The concentration-time curve in blood can be analyzed using a fluorescence detector and LC-MS/MS method. When analyzing pharmacokinetic properties, it is important to take into account the matrix effect due to human serum proteins. Desethyl chloroquine has potent inducers that affect its pharmacokinetics and metabolism, including CYP3A4 enzymes and glutathione reductase.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 291.82 g/mol
• Fórmula: C₁₆H₂₂ClN₃
• Pureza: Min. 95%
• Cor/forma: Slightly Yellow Powder
• InChI: InChI=1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
• Chave InChI: InChIKey=MCYUUUTUAAGOOT-UHFFFAOYSA-N
• SMILES: CCNCCCC(C)Nc1ccnc2cc(Cl)ccc12