Desloratadine N-hydroxypiperidine

CAS: 1193725-73-3

Ref. 3D-FD21215

Informação sobre produto

• Nome: Desloratadine N-hydroxypiperidine
• Sinónimos: 8-Chloro-6,11-dihydro-11-(1-hydroxy-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Descrição

Desloratadine N-hydroxypiperidine is a drug that is used to treat allergic rhinitis and urticaria. It belongs to the class of antihistamines, which block the activity of histamine in the body. Desloratadine N-hydroxypiperidine is a prodrug that has a piperidine moiety attached to its side chain. This prodrug is metabolized into desloratadine, its active form, by esterase enzymes in the liver and blood plasma. The onset of action is rapid after oral administration and the duration of action is 12 hours or more. Desloratadine N-hydroxypiperidine has shown linearity over a wide range of pH values (pH 1 to 10) and ionic strengths (0.1 M to 0.5 M). Optimization was achieved by adjusting elution time, ion-pairing agent, mobile phase composition, organic modifier concentration and column particle

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 326.82 g/mol
• Fórmula: C₁₉H₁₉ClN₂O
• Pureza: Min. 95%
• InChI: InChI=1S/C19H19ClN2O/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-21-19(14)18(17)13-7-10-22(23)11-8-13/h1-2,5-6,9,12,23H,3-4,7-8,10-11H2
• Chave InChI: InChIKey=AMIBINHLAUROKH-UHFFFAOYSA-N
• SMILES: ON1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1