Informação sobre produto
- 8-Chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dioneClobazam impurity A
- 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-phenyl-
- 7-Chloro-5-phenyl-1,2,4,5-tetrahydro-3H-1,5-benzodiazepine-2,4-dione
- 7-Chloro-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
- Clofazin
- Demethylclobazam
- Desmethylclobazam
- N-Demethylclobazam
- N-Desmethylclobazam
- Norclobazam
- Ver mais sinónimos
N-Desmethyl clobazam is a benzodiazepine that is metabolized by CYP3A4 and has the potential for drug interactions. When administered with CYP3A4 inducers, such as rifampin, carbamazepine, and phenytoin, plasma concentrations of clobazam can increase to potentially dangerous levels. In addition, N-desmethyl clobazam has been shown to interact with human serum proteins and may have significant interactions with other drugs. This drug has potent inducers at the liver’s cytochrome P450 enzyme system (CYP). These enzymes are responsible for metabolizing clobazam into a more active form. N-desmethyl clobazam also binds to benzodiazepine receptors in the brain and is used clinically for management of anxiety disorders in pediatric patients.
Propriedades químicas
Consulta técnica sobre: 3D-FD21253 N-Desmethyl clobazam
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