Desmethyl erlotinib carboxylate acid

CAS: 882172-60-3

Ref. 3D-FD21266

Informação sobre produto

• Nome: Desmethyl erlotinib carboxylate acid
• Sinónimos: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]

Descrição

Erlotinib is a drug that inhibits the enzyme tyrosine kinase, which is required for the growth and spread of cancer cells. It is used to treat patients with advanced non-small cell lung cancer and has been shown to have activity against other types of cancer. Erlotinib targets the epidermal growth factor receptor (EGFR), a protein that plays an important role in many cancers. Erlotinib binds to EGFR and prevents it from binding with its ligands, preventing signalling. Erlotinib also interacts with other proteins such as HER2/neu, c-kit, c-met, and PDGFRA/CD140B, which are involved in various cellular processes including proliferation, differentiation, apoptosis, and adhesion.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 393.39 g/mol
• Fórmula: C₂₁H₁₉N₃O₅
• Pureza: Min. 95%
• InChI: InChI=1S/CH4/h1H4
• Chave InChI: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCC(=O)O)cc23)c1