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4-[2-[[(1S)-1-(2-Aminophenyl)-3-methylbutyl]amino]-2-oxoethyl]-2-ethoxybenzoic acid
CAS: 637301-29-2
Ref. 3D-FD21379
| 1mg | 477,00 € | ||
| 5mg | 809,00 € | ||
| 10mg | 1.142,00 € | ||
| 25mg | 1.599,00 € | ||
| 50mg | 2.284,00 € |
Informação sobre produto
- 4-[2-[[(1S)-1-(2-Aminophenyl)-3-methylbutyl]amino]-2-oxoethyl]-2-ethoxybenzoic acidRepaglinide M1 metabolite2-Despiperidyl-2-amino repaglinide
Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.
Propriedades químicas
Consulta técnica sobre: 3D-FD21379 4-[2-[[(1S)-1-(2-Aminophenyl)-3-methylbutyl]amino]-2-oxoethyl]-2-ethoxybenzoic acid
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