2,4-Diamino-6-hydroxy-5-nitropyrimidine
CAS: 3346-23-4
Ref. 3D-FD21462
1g | 376,00 € | ||
2g | 550,00 € | ||
5g | 1.025,00 € | ||
250mg | 179,00 € | ||
500mg | 272,00 € |
Informação sobre produto
- 2,6-Diamino-5-nitroso-4-pyrimidinolNsc44924
- 2,6-Diamino-5-nitropyrimidin-4(3H)-one
- 4(3H)-pyrimidinone, 2,6-diamino-5-nitro-
2,4-Diamino-6-hydroxy-5-nitropyrimidine is an anticancer agent that has been shown to be effective against both bone and colorectal cancers. It inhibits the growth of cancer cells by inducing caspase-independent cell death, which occurs in a pd-l1 dependent manner. This agent also has minimal toxicity in vitro, as it induces cell lysis at high concentrations. 2,4-Diamino-6-hydroxy-5-nitropyrimidine is not active against normal cells.
2,4-Diamino-6-hydroxy-5-nitropyrimidine induces mitochondrial membrane depolarization and mitochondrial membrane potential loss in a dose dependent manner. These effects are likely responsible for the induction of caspase independent cell death seen with this drug.
Propriedades químicas
Consulta técnica sobre: 3D-FD21462 2,4-Diamino-6-hydroxy-5-nitropyrimidine
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.