Difethialone

CAS: 104653-34-1

Ref. 3D-FD21844

Informação sobre produto

• Nome: Difethialone
• Sinónimos: 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzothiapyran-2-one, 2H-1-Benzothiopyran-2-One,3-(3-(4’-Bromo(1,1’-Biphenyl)-4-Yl)-1,2,3,4-Tetrahyd, 2H-1-Benzothiopyran-2-one, 3-3-(4-bromo1,1-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl-4-hydroxy-, 2H-1-Benzothiopyran-2-one, 3-[3-(4′-bromo[1,1′-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-, 3-[3-(4'-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxy-4H-thiochromen-4-one, 3-[3-(4'-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxy-2H-thiochromen-2-one, 3-[3-(4′-Bromo[1,1′-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzothiopyran-2-one, Baraki, Difethiarol, Generation, Lm 2219, Lm2219, Ro-1-Naphthalenyl)-4-Hydroxy-, Rodilon
• CAS: 104653-34-1

Descrição

Difethialone is a coumarin derivative that has been used as an anticoagulant drug. It was first synthesized in 1951 and is still in use today. Difethialone inhibits the synthesis of prothrombin and other clotting factors by binding to the active site of the enzyme thrombin, which is responsible for the conversion of fibrinogen to fibrin. The long-term efficacy of difethialone has been evaluated using human serum samples with coumarin derivatives as substrates. The sample preparation, ionization techniques, and analytical methods were used to detect difethialone in human serum.

The chemical structures of difethialone are shown below:

Coumarin derivatives are organic compounds that are structurally derived from coumarin. They have many uses, such as dyeing cloth or producing fragrances.

The enantiomer of a molecule (or

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 539.48 g/mol
• Fórmula: C₃₁H₂₃BrO₂S
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C31H23BrO2S/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,34H,17-18H2
• Chave InChI: InChIKey=VSVAQRUUFVBBFS-UHFFFAOYSA-N
• SMILES: O=c1c(C2CC(c3ccc(-c4ccc(Br)cc4)cc3)Cc3ccccc32)c(O)sc2ccccc12