Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine oxide

CAS: 289042-10-0

Ref. 3D-FD22487

Informação sobre produto

• Nome: Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine oxide
• Sinónimos: N-[5-[(Diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamideRosuvastatin interm ediate Z-8.1Rosuvastatin diphenylphosphine oxide, 4-(4-Fluorophenyl)-5-(diphenylphosphinyl)methyl-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine, Methanesulfonamide, N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-, N-[5-(Diphenyl-phosphinoylmethyl)-4-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide, N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide, N-[5-[(Diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide, N-{5-[(diphenylphosphoryl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)pyrimidin-2-yl}-N-methylmethanesulfonamide, Z-8.1

Descrição

Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine oxide is an inhibitor of the reductase enzyme, which is involved in the synthesis of fatty acids. It has been shown to inhibit the growth of bacteria that are resistant to other antibiotics. The active form is a phosphine oxide and it has been shown to be an inhibitor of bacterial reductases.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 537.59 g/mol
• Fórmula: C₂₈H₂₉FN₃O₃PS
• Pureza: Min. 95%
• InChI: InChI=1S/C28H29FN3O3PS/c1-20(2)26-25(19-36(33,23-11-7-5-8-12-23)24-13-9-6-10-14-24)27(21-15-17-22(29)18-16-21)31-28(30-26)32(3)37(4,34)35/h5-18,20H,19H2,1-4H3
• Chave InChI: InChIKey=CVRDGWDBQZPJJI-UHFFFAOYSA-N
• SMILES: CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1CP(=O)(c1ccccc1)c1ccccc1