Dicoumarol

CAS: 66-76-2

Ref. 3D-FD28896

Informação sobre produto

• Nome: Dicoumarol
• Sinónimos: 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-, 3,3'-Methylenebis[4-hydroxy-1,2-benzopyrone], 3,3'-Methylenebis[4-hydroxycoumarin], 3,3′-Methylene-bis-(4-hydroxy-2H-benzopyran-2-one), 3,3′-Methylenebis(4-hydroxy-2H-chromen-2-one), 3,3′-Methylenebis[4-hydroxy-2H-1-benzopyran-2-one], Acadyl, Acavyl, Antitrombosin, Baracoumin, Bis(4-hydroxycoumarin-3-yl)methane, Bis-3,3'-(4-hydroxycoumarinyl)methane, Bishydroxycoumarin, Coumarin, 3,3'-methylenebis[4-hydroxy-, Cuma, Cumid, Di-4-hydroxy-3,3'-methylenedicoumarin, Dicoumal, Dicoumarin, Dicuman, Dicumarine, Dicumol, Dufalone, Kumoran, Melitoxin, Nc 034, Nsc 17860, Nsc 221570, Nsc 41834, Pb 2-9, Temparin, Trombosan

Descrição

Dicumarol is a coumarin derivative that inhibits the activity of polymerase chain reaction (PCR) by binding to DNA. It is also an inhibitor of nitrate reductase, which is an enzyme that catalyzes the conversion of nitrate to nitrite. Dicumarol binds to the response element on DNA and blocks the transcription of genes. This drug also has been shown to inhibit squamous cell carcinoma cells through interaction with DNA and protein thiols.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 336.30 g/mol
• Fórmula: C₁₉H₁₂O₆
• Pureza: Min. 95%
• InChI: InChI=1S/C19H12O6/c20-16-10-5-1-3-7-14(10)24-18(22)12(16)9-13-17(21)11-6-2-4-8-15(11)25-19(13)23/h1-8,20-21H,9H2
• Chave InChI: InChIKey=DOBMPNYZJYQDGZ-UHFFFAOYSA-N
• SMILES: O=c1oc2ccccc2c(O)c1Cc1c(O)c2ccccc2oc1=O