2,3-Dichloro-5-nitropyridine

CAS: 22353-40-8

Ref. 3D-FD32624

Informação sobre produto

• Nome: 2,3-Dichloro-5-nitropyridine
• Sinónimos: Pyridine, 2,3-dichloro-5-nitro-

Descrição

2,3-Dichloro-5-nitropyridine (2,3-DNP) is an antidiabetic drug that has been shown to improve insulin sensitivity in animals. It is a sample preparation reagent that can be used to validate the use of γ-aminobutyric acid (GABA) as a linker for the immobilization of proteins on solid supports. 2,3-DNP is also used as an adipose tissue marker to study obesity and insulin resistance. This drug has been shown to increase choline levels in the liver by inhibiting its export and increasing its synthesis by phosphorylation of serine hydroxymethyltransferase. 2,3-DNP also increases fatty acid synthesis by activating acetyl coenzyme A carboxylase and inhibiting carnitine palmitoyl transferase I. 2,3-DNP has also been shown to decrease food intake and body weight gain in db/db mice

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 192.99 g/mol
• Fórmula: C₅H₂Cl₂N₂O₂
• Pureza: Min. 95%
• Cor/forma: Powder