4,5-Dibromothiophene-2-carboxylic acid
CAS: 6324-10-3
Ref. 3D-FD36258
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Informação sobre produto
- 2,3-Dibromo-5-thiophenecarboxylic acid
- 2-Thiophenecarboxylic acid, 4,5-dibromo-
- 4,5-Dibromo-2-thiophenecarboxylic acid
- 4,5-Dibromothenoic acid
- NSC 30091
4,5-Dibromothiophene-2-carboxylic acid is a chiral compound that has been shown to be effective at inhibiting urokinase-type plasminogen activator (uPA) with an IC50 of about 10 nM. This inhibition is due to the postulated ability of 4,5-dibromothiophene-2-carboxylic acid to bind to the active site of uPA. The binding of 4,5-dibromothiophene-2-carboxylic acid to uPA leads to a decrease in the catalytic activity of uPA and inhibits the formation of plasmin. This decreases the production of neurokinin, which is involved in pain sensation. 4,5-Dibromothiophene-2-carboxylic acid also has pharmacokinetic properties that are similar to those seen in other pyrazole derivatives. It is selectively bound by
Propriedades químicas
Consulta técnica sobre: 3D-FD36258 4,5-Dibromothiophene-2-carboxylic acid
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