Diphenylacetic acid

CAS: 117-34-0

Ref. 3D-FD52483

Informação sobre produto

• Nome: Diphenylacetic acid
• Sinónimos: Lgc' (246)2,2-Diphenyl acetic acid, 2,2-Diphenylacetic Acid, Acetic Acid, Diphenyl-, Acide diphenylacetique, Acido Difenilacetico, Benzeneacetic acid, alpha-phenyl-, Benzeneacetic acid, α-phenyl-, Diphenylessigsaure, Diphenylethanoic acid, Nsc 120417, Nsc 8742, α,α-Diphenylacetic acid, α-Phenylbenzeneacetic acid
• CAS: 117-34-0

Descrição

Diphenylacetic acid is a chiral compound that has been shown to inhibit the synthesis of prostaglandin E2 (PGE2) and other inflammatory mediators, which play a role in autoimmune diseases. The synthesis of these mediators is dependent on the enzyme cyclooxygenase-1 (COX-1). Diphenylacetic acid inhibits COX-1 by forming an acyl ester with arachidonic acid, which blocks the formation of PGE2. This drug also inhibits COX-2 and leukotriene A4 hydrolase, which are enzymes involved in inflammation. Diphenylacetic acid has been shown to be effective in inhibiting the detrusor muscle contractions that cause urinary incontinence.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 212.24 g/mol
• Fórmula: C₁₄H₁₂O₂
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C14H12O2/c15-14(16)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13H,(H,15,16)
• Chave InChI: InChIKey=PYHXGXCGESYPCW-UHFFFAOYSA-N
• SMILES: O=C(O)C(c1ccccc1)c1ccccc1