Dimethyl Indole-2,3-Dicarboxylate
CAS: 54781-93-0
Ref. 3D-FD56778
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Informação sobre produto
- 2,3-Dicarbomethoxyindole
- Dimethyl indole-2,3-dicarboxylate
- dimethyl 1H-indole-2,3-dicarboxylate
Dimethyl Indole-2,3-Dicarboxylate is a potent inhibitor of bacterial growth. It binds to the active site of bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Dimethyl Indole-2,3-Dicarboxylate inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Dimethyl Indole-2,3-Dicarboxylate also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e
Propriedades químicas
Consulta técnica sobre: 3D-FD56778 Dimethyl Indole-2,3-Dicarboxylate
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