3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one

CAS: 5439-14-5

Ref. 3D-FD60323

Informação sobre produto

• Nome: 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one
• Sinónimos: Acid Captor H, 2H,3H,4H-Pyrido[1,2-a]pyrimidin-2-one, 2H-Pyrido[1,2-a]pyrimidin-2-one, 3,4-dihydro-, 3,4-Dihydro-2H-pyrido(1,2-a)pyrimidine-2-one, Dihydropyridopyrimidinone, NSC 15063
• CAS: 5439-14-5

Descrição

3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one is a biphenyl derivative that inhibits the HMG-CoA reductase enzyme. It is used to regulate cholesterol levels and has been shown to have a hypoglycemic effect. This drug binds to the active site of HMG-CoA reductase and prevents it from reducing HMG into mevalonate, which prevents the production of cholesterol. 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one also binds to the hydroxyl group of a thiazolidine ring and inhibits the enzyme activity of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase. This leads to an increase in endogenous insulin release and decreased blood glucose levels.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 148.16 g/mol
• Fórmula: C₈H₈N₂O
• Pureza: Min. 95%
• InChI: InChI=1S/C8H8N2O/c11-8-4-6-10-5-2-1-3-7(10)9-8/h1-3,5H,4,6H2
• Chave InChI: InChIKey=XQIOBBHIEUGFCI-UHFFFAOYSA-N
• SMILES: O=C1CCN2C=CC=CC2=N1