6,7-Dimethoxycarbostyril

CAS: 5278-38-6

Ref. 3D-FD70495

Informação sobre produto

• Nome: 6,7-Dimethoxycarbostyril
• Sinónimos: 6,7-dimethoxyquinolin-2-ol
• Marca: Biosynth
• Descrição: 6,7-Dimethoxycarbostyril is a small molecule that has been shown to induce cell death in cancer cells by inhibiting the chaperone function of heat shock protein 90 (HSP90). HSP90 is a multifunctional molecular chaperone that affects many cellular processes including cell growth, apoptosis and tumorigenesis. 6,7-Dimethoxycarbostyril binds to the ATP binding site of HSP90, preventing it from performing its chaperone role. This leads to inhibition of cell growth and induction of apoptosis. 6,7-Dimethoxycarbostyril has also been shown to inhibit tumor growth in vivo in mouse models and has successfully completed phase I clinical trials at doses up to 2000 mg/day.

Propriedades químicas

• Peso molecular: 205.21 g/mol
• Fórmula: C₁₁H₁₁NO₃
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C11H11NO3/c1-14-9-5-7-3-4-11(13)12-8(7)6-10(9)15-2/h3-6H,1-2H3,(H,12,13)
• Chave InChI: InChIKey=YCIOUNSWHDKEBM-UHFFFAOYSA-N
• SMILES: COc1cc2ccc(=O)[nH]c2cc1OC