3',3'-Difluoro-3'-Deoxythymidine

CAS: 121353-87-5

Ref. 3D-FD80516

Informação sobre produto

• Nome: 3',3'-Difluoro-3'-Deoxythymidine
• Sinónimos: 3'-Deoxy-3',3'-difluorothymidine, 3-Fluoro-1-(3'-fluoro-2',3'-dideoxy-beta-D-ribofuranosyl)-5-methyluracil, 3-Fluoro-1-(3'-fluoro-3'-deoxy-beta-D-erythropentofuranosyl)thymine, F2dT, Thymidine, 3'-deoxy-3',3'-difluoro-, 1-[(2R,5R)-4,4-difluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione

Descrição

3',3'-Difluoro-3'-Deoxythymidine is an anti-HIV drug that belongs to the group of nucleoside analogues. It is a synthetic nucleoside analogue that is structurally similar to thymidine. 3',3'-Difluoro-3'-Deoxythymidine has been shown to inhibit HIV replication in cell culture, and has shown a low incidence of resistance development. 3',3'-Difluoro-3'-Deoxythymidine inhibits HIV by competitively binding to viral reverse transcriptase, thereby blocking its activity and preventing the production of viral DNA. This drug also inhibits cellular RNA synthesis, which may be due to its inhibition of purine synthesis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 262.21 g/mol
• Fórmula: C₁₀H₁₂F₂N₂O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C10H12F2N2O4/c1-5-3-14(9(17)13-8(5)16)7-2-10(11,12)6(4-15)18-7/h3,6-7,15H,2,4H2,1H3,(H,13,16,17)/t6-,7-/m1/s1
• Chave InChI: InChIKey=JQMYGAWECCNTIR-RNFRBKRXSA-N
• SMILES: Cc1cn([C@H]2CC(F)(F)[C@@H](CO)O2)c(=O)[nH]c1=O