Informação sobre produto
- CCL11
Eotaxin is a human basic protein that belongs to the eosinophil cationic protein family. It stimulates the growth of cells and promotes tissue repair. Eotaxin also has a role in the immune response, as it is able to bind to and activate macrophages, neutrophils, and lymphocytes. Eotaxin is found in increased concentrations in inflammatory bowel disease (IBD), where it may play a role in the recruitment of inflammatory cells. The signal peptide sequence of eotaxin is cleaved by signal peptidase I and II during transit through the Golgi apparatus, yielding an active form that can be processed into mature eotaxin by several proteases. This active form can be detected by polymerase chain reaction (PCR) amplification of DNA isolated from human peripheral blood leukocytes or colonic biopsies. Eotaxin has been shown to have anti-inflammatory effects on both healthy tissues and those with
Propriedades químicas
Consulta técnica sobre: 3D-FE109314 Eotaxin (human)
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