Informação sobre produto
Nome:R-(+)-Etomoxir
Sinónimos:
- (R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid
- ethyl ester
Marca:Biosynth
Descrição:Etomoxir is a potent inhibitor of the mitochondrial enzyme, fatty acid: 2-enoyl-CoA reductase. This enzyme catalyzes the conversion of long-chain acyl-CoA to acetyl-CoA, which is required for the synthesis of mitochondrial membrane phospholipids and cardiolipin. Etomoxir inhibits this activity and consequently prevents the production of ATP. It also inhibits oxidative phosphorylation in isolated mitochondria and reduces locomotor activity in rats. Etomoxir has been shown to have inhibitory properties on human malignant brain cells as well as breast cancer cells (MDA-MB-231).
Aviso:Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Propriedades químicas
Peso molecular:326.81 g/mol
Fórmula:C17H23ClO4
Pureza:Min. 95%
InChI:InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1
Chave InChI:InChIKey=DZLOHEOHWICNIL-QGZVFWFLSA-N
SMILES:CCOC(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1