Ethyl 3-oxo-4-phenylbutanoate
CAS: 718-08-1
Ref. 3D-FE46407
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Informação sobre produto
- Benzenebutanoic Acid, Beta-Oxo-, Ethyl Ester
- 3-Oxo-4-Phenyl-Butyric Acid Ethyl Ester
Ethyl 3-oxo-4-phenylbutanoate is an impurity of the drug 4-nitrophenylacetic acid, which is used in the synthesis of the anti-cancer drug oxaliplatin. This chemical is a marker for the presence of 4-nitrophenylacetic acid and can be detected by gas chromatography. The profile of this compound includes impurities such as 2,5-dimethoxybenzoic acid and 2,5-diketopiperazine. Epidemiological studies have shown that this impurity is a potential risk factor for breast cancer. Basic hydrolysis of ethyl 3-oxo-4-phenylbutanoate has been shown to generate chloride ions and oxobutanoate ions. Chlorine ions are toxic to humans and animals and can cause respiratory irritation, nausea, vomiting, diarrhoea, convulsions, and death at high doses. Oxobutanoate ions
Propriedades químicas
Consulta técnica sobre: 3D-FE46407 Ethyl 3-oxo-4-phenylbutanoate
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