Ethyl 3-amino-4,4,4-trifluorocrotonate
CAS: 372-29-2
Ref. 3D-FE59717
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Informação sobre produto
- Ethyl 3-amino-4,4,4-trifluoro-2-butenoate3-Amino-4,4,4-trifluorocrotonic acid ethyl ester
- 2-Butenoic Acid, 3-Amino-4,4,4-Trifluoro-, Ethyl Ester
- 3-Amino-4,4,4-trifluoro-2-butenoic acid ethyl ester
- 3-Amino-4,4,4-trifluorocrotonic acid ethyl ester
- 4,4,4-Trifluoro-3-Amino crotonic acid ethylester
- Crotonic acid, 3-amino-4,4,4-trifluoro-, ethyl ester
- Ethyl 3-Amino-4,4,4-Trifluro Crotonate
- Ethyl 3-amino-4,4,4-trifluoro-2-butenoate
- Ethyl 3-amino-4,4,4-trifluorobut-2-enoate
- Ethyl 4,4,4-Trifluoro-3-Hydroxybutanoate
- Ver mais sinónimos
- ethyl (2Z)-3-amino-4,4,4-trifluorobut-2-enoate
- ethyl (3E)-4,4,4-trifluoro-3-iminobutanoate
Ethyl 3-amino-4,4,4-trifluorocrotonate is a prodrug that is metabolized by hydrolysis to the active drug ethyl trifluoroacetate. It can be used to treat disorders of the intestine such as ulcerative colitis and Crohn's disease. This prodrug has been shown to be more stable in acidic environments than other esters of trifluoroacetic acid. The drug is also used for synthesis of various pharmaceuticals. An operational profile for this drug has been developed using intestinal fluid from pigs and humans. Synthetic methods for this compound have been developed that use isopropyl alcohol as a solvent or solventless methods with ammonium sulfate as a solvent.
Propriedades químicas
Consulta técnica sobre: 3D-FE59717 Ethyl 3-amino-4,4,4-trifluorocrotonate
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