2-(4-Fluorophenyl)-1-(2-chloro-3,5-dimethoxyphenyl)-3-methyl-6-phenyl-4(1H)-pyridinone

CAS: 114231-14-0

Ref. 3D-FF101277

Informação sobre produto

• Nome: 2-(4-Fluorophenyl)-1-(2-chloro-3,5-dimethoxyphenyl)-3-methyl-6-phenyl-4(1H)-pyridinone
• Sinónimos: 1-(2-Chloro-3,5-dimethoxyphenyl)-2-(4-fluorophenyl)-3-methyl-6-phenyl-4(1H)-pyridinone, Ccris 6779, 4(1H)-Pyridinone, 1-(2-chloro-3,5-dimethoxyphenyl)-2-(4-fluorophenyl)-3-methyl-6-phenyl-, 1-(2-chloro-3,5-dimethoxyphenyl)-2-(4-fluorophenyl)-3-methyl-6-phenylpyridin-4(1H)-one
• CAS: 114231-14-0

Descrição

2-(4-Fluorophenyl)-1-(2-chloro-3,5-dimethoxyphenyl)-3-methyl-6-phenyl-4(1H)-pyridinone is a cytostatic drug that binds to the α subunit of the protein l1210 and blocks its ability to interact with the microtubules. This prevents the cell from undergoing mitosis and leads to cancer cell death. 2-(4-Fluorophenyl)-1-(2-chloro-3,5-dimethoxyphenyl)-3-methyl-6-phenyl-4(1H)-pyridinone also has an antitumor effect by inhibiting the growth of ascitic cancer cells.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 449.9 g/mol
• Fórmula: C₂₆H₂₁ClFNO₃
• Pureza: Min. 95%
• InChI: InChI=1S/C26H21ClFNO3/c1-16-23(30)15-21(17-7-5-4-6-8-17)29(26(16)18-9-11-19(28)12-10-18)22-13-20(31-2)14-24(32-3)25(22)27/h4-15H,1-3H3
• Chave InChI: InChIKey=MYSNSNGSKLLDBP-UHFFFAOYSA-N
• SMILES: COc1cc(OC)c(Cl)c(-n2c(-c3ccccc3)cc(=O)c(C)c2-c2ccc(F)cc2)c1