2-Fluoro-5-methoxy-4-nitrobenzoic acid
CAS: 1001345-80-7
Ref. 3D-FF143403
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Informação sobre produto
2-Fluoro-5-methoxy-4-nitrobenzoic acid is a molecule inhibitor that inhibits the activity of Plk1, a protein that is involved in cell division. It has been shown to be effective against solid malignancies such as breast, prostate and ovarian cancers. 2-Fluoro-5-methoxy-4-nitrobenzoic acid is an optimized small molecule that was discovered using structure based drug design. The compound binds to the ATP binding site of Plk1 and prevents ATP from binding, which leads to inhibition of the kinase activity. 2FMBA also inhibits the growth of cells by disrupting mitosis through interference with microtubule formation. This drug can be taken orally and has demonstrated good tolerability in clinical trials.
Propriedades químicas
Consulta técnica sobre: 3D-FF143403 2-Fluoro-5-methoxy-4-nitrobenzoic acid
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