4-[3-[3-[4-(4-Fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-2-pyrrolizinone

CAS: 73725-85-6

Ref. 3D-FF145518

Informação sobre produto

• Nome: 4-[3-[3-[4-(4-Fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-2-pyrrolizinone
• Sinónimos: Lidanserin, (+-)-4-(3-(3-(4-(p-Fluorobenzoyl)piperidino)propoxy)-4-methoxyphenyl)-2-pyrrolidinone, 2-Pyrrolidinone, 4-(3-(3-(4-(p-fluorobenzoyl)piperidino)propoxy)-4-methoxyphenyl)-, (+-)-, 2-Pyrrolidinone, 4-[3-[3-[4-(4-fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-, 4-(3-{3-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Propoxy}-4-Methoxyphenyl)Pyrrolidin-2-One, 4-[3-[3-[4-(4-Fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-2-pyrrolidinone, Lidanserin [INN], Lidanserina, Lidanserina [INN-Spanish], Lidanserine, Lidanserine [INN-French], Lidanserinum, Lidanserinum [INN-Latin], Unii-80O1E9Jzln, Zk 33839

Descrição

4-[3-[3-[4-(4-Fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-2-pyrrolizinone is a linker that is used for drug conjugation. It has been shown to inhibit the activity of serotonergic enzymes and to be an effective cancer drug. 4-[3-[3-[4-(4-Fluorobenzoyl)-1-piperidinyl]propoxy]-4-methoxyphenyl]-2-pyrrolizinone also has high concentrations in hyperproliferative diseases, such as cancer or psoriasis, and can be used as a diluent for drugs. This compound inhibits oxidative phosphorylation by binding to cytochrome c oxidase and other targets involved in the electron transport chain in mitochondria. It also binds to the enzyme protein kinase C, which regulates cell proliferation

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 454.53 g/mol
• Fórmula: C₂₆H₃₁FN₂O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C26H31FN2O4/c1-32-23-8-5-20(21-16-25(30)28-17-21)15-24(23)33-14-2-11-29-12-9-19(10-13-29)26(31)18-3-6-22(27)7-4-18/h3-8,15,19,21H,2,9-14,16-17H2,1H3,(H,28,30)
• Chave InChI: InChIKey=JDYWZVJXSMADHP-UHFFFAOYSA-N
• SMILES: COc1ccc(C2CNC(=O)C2)cc1OCCCN1CCC(C(=O)c2ccc(F)cc2)CC1