Informação sobre produto
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- 1,3,5-triazin-2(1H)-one, 4-amino-1-beta-D-arabinofuranosyl-
- 1-.beta.-D-Arabinofuranosyl-5-azacytosine
- 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-azacytosine
- 1b-D-Arabinofuranosyl-5-azacytosine
- 4-Amino-1-(beta-D-arabinofuranosyl)-1,3,5-triazin-2(1H)-one
- 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,3,5-triazin-2(1H)-one
- 4-Amino-1b-D-arabinofuranosyl-s-triazin-2(1H)-one
- 5-Aza-1-arabinosylcytosine
- 5-Azacytosine arabinoside
- Ver mais sinónimos
- 65886-71-7
- Kymarabine
- NSC 281272
- ara-AC
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-arabinofuranosyl-
- 4-Amino-1-β-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one
- 1-β-D-Arabinofuranosyl-5-azacytosine
Fazarabine is a nucleoside analog that has been shown to be a potent inhibitor of the enzyme fyn tyrosine kinase and to have cytotoxic effects on human leukemia HL-60 cells. The chemical stability of fazarabine has been demonstrated in methyltransferase inhibition studies. Fazarabine is also an anti-cancer compound with selective toxicity towards colorectal adenocarcinoma cells. Fazarabine inhibits cell proliferation by inhibiting protein synthesis, which may be due to its ability to act as a DNA template, or its receptor activity. Fazarabine also has immunosuppressive properties and can be used for the treatment of autoimmune diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis.
Propriedades químicas
Consulta técnica sobre: 3D-FF157115 Fazarabine
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