Formamidine acetate

CAS: 3473-63-0

Ref. 3D-FF38201

Informação sobre produto

• Nome: Formamidine acetate
• Sinónimos: Acetic acid methanimidamide, Formamidine acetate (1:1), Formamidine acetate salt, Formamidine acetic acid salt, Formamidine, monoacetate, Formamidinium acetate, Formimidamide acetate, Imidoformamide Acetate (1:1), Iminoformamide acetate, Methanimidamide Acetate, Methanimidamide monoacetate, Methanimidamide, acetate (1:1), Methyl 4-Methyl-1,3-Thiazole-5-Carboxylate, NSC 96608

Descrição

Formamidine acetate is an anti-tuberculosis drug that belongs to the class of aminoglycosides. It has been shown to have a potent cytotoxic effect on malignant brain cells in vitro. Formamidine acetate inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Formamidine acetate also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 104.11 g/mol
• Fórmula: C₂H₄O₂•CH₄N₂
• Pureza: Min. 95%
• Cor/forma: Off-White Clear Liquid
• InChI: InChI=1S/C2H4O2.CH4N2/c1-2(3)4;2-1-3/h1H3,(H,3,4);1H,(H3,2,3)
• Chave InChI: InChIKey=XPOLVIIHTDKJRY-UHFFFAOYSA-N
• SMILES: CC(=O)O.N=CN