4-Fluoro-1-cyclohexanecarboxylicacid

CAS: 95233-41-3

Ref. 3D-FF45141

Informação sobre produto

• Nome: 4-Fluoro-1-cyclohexanecarboxylicacid

Descrição

4-Fluoro-1-cyclohexanecarboxylic acid is a serotonin receptor ligand that binds to the 5-HT1A receptor. It is used as a radioligand for positron emission tomography (PET) imaging of the 5-HT1A receptor in animal and human studies. 4-Fluoro-1-cyclohexanecarboxylic acid has been shown to have high affinity for the 5-HT1A receptor, with an intercept of 0.14 nM at the highest concentration tested (100 μM). This drug has been shown to have good pharmacokinetic properties in rats, with a half life of 1.5 hours and a volume of distribution of 2.3 L/kg. 4-Fluoro-1-cyclohexanecarboxylic acid also has biological properties that are not shared by other drugs, including uptake by rat hepatocytes.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 146.16 g/mol
• Fórmula: C₇H₁₁FO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C7H11FO2/c8-6-3-1-5(2-4-6)7(9)10/h5-6H,1-4H2,(H,9,10)
• Chave InChI: InChIKey=IUMDEBKXOXPBEX-UHFFFAOYSA-N
• SMILES: O=C(O)C1CCC(F)CC1