4-[(R,S)-α-1-(9H-Fluren-9-yl)-methoxy formamido]2,4-dimethoxybenzylphenoxyacetic acid

CAS: 126828-35-1

Ref. 3D-FF47654

Informação sobre produto

• Nome: 4-[(R,S)-α-1-(9H-Fluren-9-yl)-methoxy formamido]2,4-dimethoxybenzylphenoxyacetic acid
• Sinónimos: Fmoc-Rink amide linkerKnorr Linker, Acetic acid, [4-[(2,4-dimethoxyphenyl)[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]phenoxy]-, 2-[4-[(2,4-Dimethoxyphenyl)[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]phenoxy]acetic acid, FMOC-AM, Acetic acid, 2-[4-[(2,4-dimethoxyphenyl)[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]phenoxy]-, Fmoc-Knorr, 4-[(2,4-Dimethoxyphenyl)[(9H-fluoren-9-ylmethoxy) carbonylamino]methyl]phenoxyacetic Acid

Descrição

4-[(R,S)-alpha-1-(9H-Fluren-9-yl)-methoxy formamido]2,4-dimethoxybenzylphenoxyacetic acid is an amide that inhibits the activity of certain enzymes. It binds to peptides and polypeptides by binding to a functional group on the protein. This compound is a potent inhibitor of the enzyme dipeptidyl peptidase IV (DPPIV). DPPIV is responsible for cleaving dipeptides from the N terminus of proteins at the site of aspartic acid, leading to degradation of proteins. 4-[(R,S)-alpha-1-(9H-Fluren-9-yl)-methoxy formamido]2,4-dimethoxybenzylphenoxyacetic acid does not inhibit human liver DPPIV at concentrations up to 10 μM.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 539.58 g/mol
• Fórmula: C₃₂H₂₉NO₇
• Pureza: Min. 95%
• InChI: InChI=1S/C32H29NO7/c1-37-22-15-16-27(29(17-22)38-2)31(20-11-13-21(14-12-20)39-19-30(34)35)33-32(36)40-18-28-25-9-5-3-7-23(25)24-8-4-6-10-26(24)28/h3-17,28,31H,18-19H2,1-2H3,(H,33,36)(H,34,35)
• Chave InChI: InChIKey=UPMGJEMWPQOACJ-UHFFFAOYSA-N
• SMILES: COc1ccc(C(NC(=O)OCC2c3ccccc3-c3ccccc32)c2ccc(OCC(=O)O)cc2)c(OC)c1