Fmoc-L-aspartic acid alpha-amide

CAS: 200335-40-6

Ref. 3D-FF47871

Informação sobre produto

• Nome: Fmoc-L-aspartic acid alpha-amide
• Sinónimos: Fmoc-L-Asp-NH2Fmoc-L-isoasparagine, N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alpha-asparagine, Fmoc-L-Isoasparagine
• CAS: 200335-40-6

Descrição

Fmoc-L-aspartic acid alpha-amide is a prodrug that is activated by hydrolysis in the presence of a cysteine residue. It inhibits protein synthesis by binding to the active site of the enzyme and modifying it, thereby preventing formation of peptide bonds. Fmoc-L-aspartic acid alpha-amide has been shown to be more stable than other aspartic acids because it contains an alpha amide group at its N terminus, which can be cleaved by enzymes and thus easily metabolized. Fmoc-L-aspartic acid alpha-amide is also resistant to proteolytic degradation due to its covalent nature. The modification of the active site allows for selective inhibition of specific proteins involved in inflammation and downregulation of immune responses.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 354.36 g/mol
• Fórmula: C₁₉H₁₈N₂O₅
• Pureza: Min. 95%
• InChI: InChI=1S/C19H18N2O5/c20-18(24)16(9-17(22)23)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,24)(H,21,25)(H,22,23)/t16-/m0/s1
• Chave InChI: InChIKey=VHRMWRHTRSQVJJ-INIZCTEOSA-N
• SMILES: NC(=O)[C@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21