5-Fluoroindole-2-carboxylic acid methyl ester
CAS: 167631-84-7
Ref. 3D-FF56772
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Informação sobre produto
- 5-Fluoro-1H-indole-2-carboxylic acid methyl esterMethyl 5-fluoro-1H-indole-2-carboxylate
- Cbi-Bb Zero/005614
- Methyl 5-Fluoroindole-2-Carboxylate
- Akos Jy2083270
- 5-Fluoroindole-2-Carboxylic Acid Methyl Ester
- methyl 5-fluoro-1H-indole-2-carboxylate
5-Fluoroindole-2-carboxylic acid methyl ester (5FCM) is a potent and selective diabetogenic agent that is currently under development for the treatment of type 2 diabetes. 5FCM binds to the active site of pancreatic α-amylase, inhibiting its function and reducing blood glucose levels. It has been shown to have a good safety profile in animal studies. The kinetic parameters for 5FCM are determined by measuring the effect of this drug on pancreatic α-amylase activity. These parameters include the inhibition constant KI, which is an indicator for potency, and the inhibition rate constant kI, which determines how quickly 5FCM inhibits pancreatic α-amylase activity. The interaction between 5FCM and pancreatic α-amylase has been studied using molecular modeling techniques.
Propriedades químicas
Consulta técnica sobre: 3D-FF56772 5-Fluoroindole-2-carboxylic acid methyl ester
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