2-Fluoro-3-methoxybenzoic acid

CAS: 137654-20-7

Ref. 3D-FF73244

Informação sobre produto

• Nome: 2-Fluoro-3-methoxybenzoic acid
• Sinónimos: 2-Fluoro-3-methoxybenzoic acid 98%, 2-Fluoro-3-methoxybenzoicacid98%, 2-Fluoro-3-Methoxybenzoate

Descrição

2-Fluoro-3-methoxybenzoic acid (2FMBA) is an intramolecular lithiated compound that has been shown to be a potent inhibitor of the enzyme Dihydrofolate reductase. It is synthesized by reacting lithiated fluorobenzenes with methoxide ions in an aqueous solution at pH 10. The synthesis yields are improved by using lithium diisopropylamide as the base and 2FMBA as the product. Experiments have shown that 2FMBA inhibits bacterial growth, binds to DNA, and inhibits RNA synthesis in bacteria.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 170.14 g/mol
• Fórmula: C₈H₇FO₃
• Pureza: Min. 95%
• InChI: InChI=1S/C8H7FO3/c1-12-6-4-2-3-5(7(6)9)8(10)11/h2-4H,1H3,(H,10,11)
• Chave InChI: InChIKey=AVGWCJLTQZQLCN-UHFFFAOYSA-N
• SMILES: COc1cccc(C(=O)O)c1F