2-Fluoroestradiol

CAS: 16205-32-6

Ref. 3D-FF77149

Informação sobre produto

• Nome: 2-Fluoroestradiol
• Sinónimos: Nsc 97849, Estra-1,3,5(10)-triene-3,17-diol, 2-fluoro-, (17beta)-, (17Beta)-2-Fluoroestra-1(10),2,4-Triene-3,17-Diol, 2-Fluoroestra-1(10),2,4-Triene-3,17-Diol

Descrição

2-Fluoroestradiol is a synthetic form of 17β-estradiol that has been shown to inhibit the growth of tumor cells in an experimental model. 2-Fluoroestradiol binds to the estrogen receptor and inhibits the production of proteins needed for cell division, thus causing cancer. This drug has also been shown to inhibit lipoprotein lipase activity in rat liver microsomes, which may be due to its ability to induce chemical reactions. In addition, 2-fluoroestradiol inhibits lipid synthesis in fat cells and decreases lipogenesis in granulosa cells from ovaries. The inhibition of triglyceride synthesis by 2-fluoroestradiol is probably due to its ability to inhibit enzyme induction and increase the expression of mRNA for protein synthesis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 290.37 g/mol
• Fórmula: C₁₈H₂₃FO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C18H23FO2/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-16(20)15(19)9-13(10)11/h8-9,11-12,14,17,20-21H,2-7H2,1H3
• Chave InChI: InChIKey=HDPXSAXRLVDBIR-UHFFFAOYSA-N
• SMILES: CC12CCC3c4cc(F)c(O)cc4CCC3C1CCC2O